1gp1

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[[Image:1gp1.gif|left|200px]]<br /><applet load="1gp1" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1gp1, resolution 2.0&Aring;" />
 
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'''THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION'''<br />
 
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==About this Structure==
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==THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION==
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1GP1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Active as [http://en.wikipedia.org/wiki/Glutathione_peroxidase Glutathione peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.9 1.11.1.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GP1 OCA].
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<StructureSection load='1gp1' size='340' side='right'caption='[[1gp1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1gp1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. The August 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Selenocysteine Synthase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_8 10.2210/rcsb_pdb/mom_2008_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GP1 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SE7:2-AMINO-3-SELENINO-PROPIONIC+ACID'>SE7</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gp1 OCA], [https://pdbe.org/1gp1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gp1 RCSB], [https://www.ebi.ac.uk/pdbsum/1gp1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gp1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GPX1_BOVIN GPX1_BOVIN] Protects the hemoglobin in erythrocytes from oxidative breakdown.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gp/1gp1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gp1 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution., Epp O, Ladenstein R, Wendel A, Eur J Biochem. 1983 Jun 1;133(1):51-69. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6852035 6852035]
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*[[Glutathione peroxidase|Glutathione peroxidase]]
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[[Category: Glutathione peroxidase]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Epp, O.]]
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[[Category: Bos taurus]]
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[[Category: Ladenstein, R.]]
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[[Category: Large Structures]]
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[[Category: oxidoreductase(h2o2(a))]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Selenocysteine Synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:52:30 2008''
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[[Category: Epp O]]
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[[Category: Ladenstein R]]

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THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION

PDB ID 1gp1

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