3qc9

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[[Image:3qc9.png|left|200px]]
 
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{{STRUCTURE_3qc9| PDB=3qc9 | SCENE= }}
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==Crystal structure of cross-linked bovine GRK1 T8C/N480C double mutant complexed with ADP and Mg==
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<StructureSection load='3qc9' size='340' side='right'caption='[[3qc9]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===Crystal structure of cross-linked bovine GRK1 T8C/N480C double mutant complexed with ADP and Mg===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qc9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QC9 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21265573}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qc9 OCA], [https://pdbe.org/3qc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qc9 RCSB], [https://www.ebi.ac.uk/pdbsum/3qc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qc9 ProSAT]</span></td></tr>
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[[3qc9]] is a 4 chain structure of [[Rhodopsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QC9 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GRK1_BOVIN GRK1_BOVIN] Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed:12686556, PubMed:16675451, PubMed:21299498). This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (By similarity). May play a role in the maintenance of the outer nuclear layer in the retina (By similarity).[UniProtKB:Q9WVL4]<ref>PMID:12686556</ref> <ref>PMID:16675451</ref> <ref>PMID:21299498</ref>
==See Also==
==See Also==
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*[[Rhodopsin|Rhodopsin]]
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*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
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*[[Rhodopsin kinase|Rhodopsin kinase]]
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==Reference==
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== References ==
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<ref group="xtra">PMID:021265573</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Rhodopsin kinase]]
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[[Category: Large Structures]]
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[[Category: Huang, C C.]]
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[[Category: Huang C-C]]
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[[Category: Tesmer, J J.G.]]
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[[Category: Tesmer JJG]]
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[[Category: Enkaryotic protein kinase fold]]
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[[Category: Protein serine/threonine kinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of cross-linked bovine GRK1 T8C/N480C double mutant complexed with ADP and Mg

PDB ID 3qc9

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