1sh6
From Proteopedia
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| - | [[Image:1sh6.png|left|200px]] | ||
| - | + | ==Crystal structure of actin-binding domain of mouse plectin== | |
| - | + | <StructureSection load='1sh6' size='340' side='right'caption='[[1sh6]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1sh6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SH6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sh6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sh6 OCA], [https://pdbe.org/1sh6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sh6 RCSB], [https://www.ebi.ac.uk/pdbsum/1sh6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sh6 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1sh6]] is a 1 chain structure | + | == Function == |
| + | [https://www.uniprot.org/uniprot/PLEC_MOUSE PLEC_MOUSE] Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. May be involved not only in the cross-linking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sh/1sh6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sh6 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Plectin|Plectin]] | *[[Plectin|Plectin]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Sevcik | + | [[Category: Sevcik J]] |
| - | [[Category: Urbanikova | + | [[Category: Urbanikova L]] |
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Current revision
Crystal structure of actin-binding domain of mouse plectin
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