3raj

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[[Image:3raj.png|left|200px]]
 
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{{STRUCTURE_3raj| PDB=3raj | SCENE= }}
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==Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7==
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<StructureSection load='3raj' size='340' side='right'caption='[[3raj]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
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===Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3raj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RAJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.044&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3raj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3raj OCA], [https://pdbe.org/3raj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3raj RCSB], [https://www.ebi.ac.uk/pdbsum/3raj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3raj ProSAT]</span></td></tr>
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[[3raj]] is a 3 chain structure of [[Antibody]] and [[Cluster of Differentiation 38]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RAJ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CD38_HUMAN CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Cluster of Differentiation 38|Cluster of Differentiation 38]]
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*[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Hao, Q.]]
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[[Category: Hao Q]]
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[[Category: Lee, H C.]]
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[[Category: Lee HC]]
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[[Category: Zhang, H.]]
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[[Category: Zhang H]]
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[[Category: Adp-ribosyl cyclase]]
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[[Category: Agonistic antibody]]
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[[Category: Calcium signaling]]
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[[Category: Cd38]]
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[[Category: Cyclic adp-ribose]]
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[[Category: Hb7]]
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[[Category: Hydrolase-immune system complex]]
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[[Category: X-crystallography]]
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Current revision

Crystal structure of human CD38 in complex with the Fab fragment of antibody HB7

PDB ID 3raj

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