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1ewe

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[[Image:1ewe.png|left|200px]]
 
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{{STRUCTURE_1ewe| PDB=1ewe | SCENE= }}
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==Fructose 1,6-Bisphosphate Aldolase from Rabbit Muscle==
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<StructureSection load='1ewe' size='340' side='right'caption='[[1ewe]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===Fructose 1,6-Bisphosphate Aldolase from Rabbit Muscle===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ewe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EWE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11779856}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ewe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ewe OCA], [https://pdbe.org/1ewe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ewe RCSB], [https://www.ebi.ac.uk/pdbsum/1ewe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ewe ProSAT]</span></td></tr>
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[[1ewe]] is a 4 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EWE OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALDOA_RABIT ALDOA_RABIT] Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.<ref>PMID:17329259</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/1ewe_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ewe ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aldolase|Aldolase]]
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:011779856</ref><references group="xtra"/>
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__TOC__
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[[Category: Fructose-bisphosphate aldolase]]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Maurady, A.]]
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[[Category: Maurady A]]
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[[Category: Sygusch, J.]]
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[[Category: Sygusch J]]
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[[Category: Aldolase]]
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[[Category: Alpha/beta barrel]]
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[[Category: Glycolisis]]
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[[Category: Lyase]]
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[[Category: Schiff base]]
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Current revision

Fructose 1,6-Bisphosphate Aldolase from Rabbit Muscle

PDB ID 1ewe

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