1unk

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[[Image:1unk.png|left|200px]]
 
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{{STRUCTURE_1unk| PDB=1unk | SCENE= }}
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==STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN==
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<StructureSection load='1unk' size='340' side='right'caption='[[1unk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1unk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UNK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9135159}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1unk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1unk OCA], [https://pdbe.org/1unk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1unk RCSB], [https://www.ebi.ac.uk/pdbsum/1unk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1unk ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1unk]] is a 4 chain structure of [[Colicin]] and [[Colicin Immunity Protein]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UNK OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/un/1unk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1unk ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Colicin|Colicin]]
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*[[Colicin 3D structures|Colicin 3D structures]]
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*[[Colicin Immunity Protein|Colicin Immunity Protein]]
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*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009135159</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Chak, K F.]]
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[[Category: Large Structures]]
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[[Category: Hsieh, S Y.]]
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[[Category: Chak K-F]]
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[[Category: Ko, T P.]]
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[[Category: Hsieh S-Y]]
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[[Category: Ku, W Y.]]
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[[Category: Ko T-P]]
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[[Category: Tseng, M Y.]]
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[[Category: Ku W-Y]]
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[[Category: Yuan, H S.]]
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[[Category: Tseng M-Y]]
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[[Category: Dimeric structure]]
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[[Category: Yuan HS]]
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[[Category: Immunity protein]]
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[[Category: Rnase active site]]
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STRUCTURE OF COLICIN E7 IMMUNITY PROTEIN

PDB ID 1unk

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