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1c12

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[[Image:1c12.png|left|200px]]
 
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{{STRUCTURE_1c12| PDB=1c12 | SCENE= }}
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==INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE==
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<StructureSection load='1c12' size='340' side='right'caption='[[1c12]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1c12]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C12 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10525411}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRZ:TRAZEOLIDE'>TRZ</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c12 OCA], [https://pdbe.org/1c12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c12 RCSB], [https://www.ebi.ac.uk/pdbsum/1c12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c12 ProSAT]</span></td></tr>
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[[1c12]] is a 2 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C12 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IGKC_MOUSE IGKC_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/1c12_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c12 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010525411</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Anguille, C.]]
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[[Category: Anguille C]]
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[[Category: Butenandt, J.]]
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[[Category: Butenandt J]]
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[[Category: Cambillau, C.]]
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[[Category: Cambillau C]]
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[[Category: Hermans, P.]]
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[[Category: Hermans P]]
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[[Category: Honegger, A.]]
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[[Category: Honegger A]]
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[[Category: Langedijk, A C.]]
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[[Category: Langedijk AC]]
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[[Category: Nederlof, J.]]
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[[Category: Nederlof J]]
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[[Category: Pluckthun, A.]]
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[[Category: Pluckthun A]]
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[[Category: Spinelli, S.]]
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[[Category: Spinelli S]]
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[[Category: Antibody-antigen complex]]
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[[Category: Cdrh3]]
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[[Category: Immune system]]
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[[Category: Musk odorant]]
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[[Category: Odorant specificity]]
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[[Category: Scfv fragment]]
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Current revision

INSIGHT IN ODORANT PERCEPTION: THE CRYSTAL STRUCTURE AND BINDING CHARACTERISTICS OF ANTIBODY FRAGMENTS DIRECTED AGAINST THE MUSK ODORANT TRASEOLIDE

PDB ID 1c12

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