2j27
From Proteopedia
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- | [[Image:2j27.png|left|200px]] | ||
- | + | ==The functional role of the conserved active site proline of triosephosphate isomerase== | |
- | + | <StructureSection load='2j27' size='340' side='right'caption='[[2j27]], [[Resolution|resolution]] 1.15Å' scene=''> | |
- | === | + | == Structural highlights == |
- | + | <table><tr><td colspan='2'>[[2j27]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J27 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGA:2-PHOSPHOGLYCOLIC+ACID'>PGA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j27 OCA], [https://pdbe.org/2j27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j27 RCSB], [https://www.ebi.ac.uk/pdbsum/2j27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j27 ProSAT]</span></td></tr> |
- | [[2j27]] is a 2 chain structure | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TPIS_TRYBB TPIS_TRYBB] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/2j27_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j27 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | + | *[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]] | |
- | *[[Triose | + | __TOC__ |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
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- | [[Category: | + | |
[[Category: Trypanosoma brucei brucei]] | [[Category: Trypanosoma brucei brucei]] | ||
- | [[Category: Alahuhta | + | [[Category: Alahuhta M]] |
- | [[Category: Augustyns | + | [[Category: Augustyns K]] |
- | [[Category: Casteleijn | + | [[Category: Casteleijn MG]] |
- | [[Category: El-Sayed | + | [[Category: El-Sayed I]] |
- | [[Category: Groebel | + | [[Category: Groebel K]] |
- | [[Category: Lambeir | + | [[Category: Lambeir AM]] |
- | [[Category: Neubauer | + | [[Category: Neubauer P]] |
- | [[Category: Wierenga | + | [[Category: Wierenga RK]] |
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Current revision
The functional role of the conserved active site proline of triosephosphate isomerase
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