1gxg
From Proteopedia
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| - | [[Image:1gxg.gif|left|200px]]<br /><applet load="1gxg" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1gxg" /> | ||
| - | '''NON-COGNATE PROTEIN-PROTEIN INTERACTIONS: THE NMR STRUCTURE OF THE COLICIN E8 INHIBITOR PROTEIN IM8 AND ITS INTERACTION WITH THE DNASE DOMAIN OF COLICIN E9'''<br /> | ||
| - | == | + | ==Non-cognate protein-protein interactions: the NMR structure of the colicin E8 inhibitor protein Im8 and its interaction with the DNase domain of colicin E9== |
| - | + | <StructureSection load='1gxg' size='340' side='right'caption='[[1gxg]]' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1gxg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1imz 1imz]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXG FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxg OCA], [https://pdbe.org/1gxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxg RCSB], [https://www.ebi.ac.uk/pdbsum/1gxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxg ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/IMM8_ECOLX IMM8_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE8 encoding colicin E8, against colicin E8, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. | |
| - | [ | + | == Evolutionary Conservation == |
| - | [[ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [ | + | Check<jmol> |
| - | [[ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxg_consurf.spt"</scriptWhenChecked> |
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxg ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Boetzel R]] | ||
| + | [[Category: Czisch M]] | ||
| + | [[Category: James R]] | ||
| + | [[Category: Kleanthous C]] | ||
| + | [[Category: Le Duff CS]] | ||
| + | [[Category: Moore GR]] | ||
| + | [[Category: Videler H]] | ||
Current revision
Non-cognate protein-protein interactions: the NMR structure of the colicin E8 inhibitor protein Im8 and its interaction with the DNase domain of colicin E9
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