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3lz6

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[[Image:3lz6.png|left|200px]]
 
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{{STRUCTURE_3lz6| PDB=3lz6 | SCENE= }}
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==Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423==
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<StructureSection load='3lz6' size='340' side='right'caption='[[3lz6]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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===Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3lz6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cavia_porcellus Cavia porcellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZ6 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20363126}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A0D:N-ADAMANTAN-2-YL-1-ETHYL-D-PROLINAMIDE'>A0D</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lz6 OCA], [https://pdbe.org/3lz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lz6 RCSB], [https://www.ebi.ac.uk/pdbsum/3lz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lz6 ProSAT]</span></td></tr>
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[[3lz6]] is a 4 chain structure of [[Hydroxysteroid dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Cavia_porcellus Cavia porcellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZ6 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHI1_CAVPO DHI1_CAVPO] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).<ref>PMID:10699594</ref>
==See Also==
==See Also==
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*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]
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*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:020363126</ref><references group="xtra"/>
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__TOC__
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[[Category: 11-beta-hydroxysteroid dehydrogenase]]
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</StructureSection>
[[Category: Cavia porcellus]]
[[Category: Cavia porcellus]]
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[[Category: Pauly, T A.]]
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[[Category: Large Structures]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Pauly TA]]

Current revision

Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423

PDB ID 3lz6

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