1inq

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[[Image:1inq.png|left|200px]]
 
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{{STRUCTURE_1inq| PDB=1inq | SCENE= }}
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==Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db==
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<StructureSection load='1inq' size='340' side='right'caption='[[1inq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1inq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1INQ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11751972}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1inq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1inq OCA], [https://pdbe.org/1inq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1inq RCSB], [https://www.ebi.ac.uk/pdbsum/1inq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1inq ProSAT]</span></td></tr>
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[[1inq]] is a 3 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INQ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/in/1inq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1inq ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:011751972</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Christianson, G J.]]
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[[Category: Christianson GJ]]
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[[Category: Grey, H.]]
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[[Category: Grey H]]
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[[Category: Mendoza, L.]]
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[[Category: Mendoza L]]
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[[Category: Nathenson, S G.]]
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[[Category: Nathenson SG]]
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[[Category: Ostrov, D A.]]
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[[Category: Ostrov DA]]
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[[Category: Palmieri, E.]]
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[[Category: Palmieri E]]
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[[Category: Roden, M M.]]
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[[Category: Roden MM]]
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[[Category: Roopenian, D.]]
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[[Category: Roopenian D]]
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[[Category: Shastri, N.]]
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[[Category: Shastri N]]
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[[Category: Shi, W.]]
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[[Category: Shi W]]
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[[Category: Tilley, D.]]
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[[Category: Tilley D]]
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[[Category: Villaflor, G.]]
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[[Category: Villaflor G]]
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[[Category: Immune system]]
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[[Category: Mhc complex]]
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[[Category: Minor histocompatibility antigen]]
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Current revision

Structure of Minor Histocompatibility Antigen peptide, H13a, complexed to H2-Db

PDB ID 1inq

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