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1gku

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[[Image:1gku.png|left|200px]]
 
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{{STRUCTURE_1gku| PDB=1gku | SCENE= }}
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==Reverse gyrase from Archaeoglobus fulgidus==
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<StructureSection load='1gku' size='340' side='right'caption='[[1gku]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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===REVERSE GYRASE FROM ARCHAEOGLOBUS FULGIDUS===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1gku]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GKU FirstGlance]. <br>
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{{ABSTRACT_PUBMED_11823434}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gku OCA], [https://pdbe.org/1gku PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gku RCSB], [https://www.ebi.ac.uk/pdbsum/1gku PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gku ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1gku]] is a 1 chain structure of [[Gyrase]] with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GKU OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/RGYR_ARCFU RGYR_ARCFU] Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gku_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gku ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Gyrase|Gyrase]]
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:011823434</ref><references group="xtra"/>
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[[Category: Archaeoglobus fulgidus DSM 4304]]
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[[Category: Archaeoglobus fulgidus]]
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[[Category: Large Structures]]
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[[Category: Rodriguez, A C.]]
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[[Category: Rodriguez AC]]
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[[Category: Stock, D.]]
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[[Category: Stock D]]
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[[Category: Archaea]]
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[[Category: Dna supercoiling]]
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[[Category: Helicase]]
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[[Category: Topoisomerase]]
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Current revision

Reverse gyrase from Archaeoglobus fulgidus

PDB ID 1gku

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