3ae6

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[[Image:3ae6.png|left|200px]]
 
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{{STRUCTURE_3ae6| PDB=3ae6 | SCENE= }}
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==Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid==
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<StructureSection load='3ae6' size='340' side='right'caption='[[3ae6]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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===Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ae6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AE6 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=JMP:2-{[3-(1-METHYLETHOXY)PHENYL]CARBAMOYL}BENZOIC+ACID'>JMP</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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[[3ae6]] is a 4 chain structure of [[Succinate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE6 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ae6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ae6 OCA], [https://pdbe.org/3ae6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ae6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ae6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ae6 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).
==See Also==
==See Also==
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*[[Succinate Dehydrogenase|Succinate Dehydrogenase]]
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*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Harada, S.]]
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[[Category: Harada S]]
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[[Category: Honma, T.]]
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[[Category: Honma T]]
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[[Category: Inaoka, D K.]]
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[[Category: Inaoka DK]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kido, Y.]]
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[[Category: Kido Y]]
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[[Category: Kita, K.]]
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[[Category: Kita K]]
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[[Category: Mao, J.]]
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[[Category: Mao J]]
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[[Category: Matsuoka, S.]]
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[[Category: Matsuoka S]]
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[[Category: Omori, J.]]
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[[Category: Omori J]]
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[[Category: Osanai, A.]]
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[[Category: Osanai A]]
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[[Category: Sakamoto, K.]]
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[[Category: Sakamoto K]]
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[[Category: Sasaki, T.]]
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[[Category: Sasaki T]]
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[[Category: Shindo, M.]]
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[[Category: Shindo M]]
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[[Category: Tanaka, A.]]
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[[Category: Tanaka A]]
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[[Category: Electron transport]]
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[[Category: Fad-binding protein]]
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[[Category: Heme]]
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[[Category: Inhibitor]]
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[[Category: Iron]]
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[[Category: Iron-sulfur]]
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[[Category: Metal-binding]]
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[[Category: Mitochondrion]]
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[[Category: Mitochondrion inner membrane]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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[[Category: Respiratory complex ii]]
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[[Category: Transit peptide]]
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[[Category: Transmembrane]]
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[[Category: Transport]]
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[[Category: Tricarboxylic acid cycle]]
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Current revision

Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Isopropoxy-phenyl)-phthalamicacid

PDB ID 3ae6

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