3ccq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:34, 21 February 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3ccq.png|left|200px]]
 
-
{{STRUCTURE_3ccq| PDB=3ccq | SCENE= }}
+
==Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U==
-
 
+
<StructureSection load='3ccq' size='340' side='right'caption='[[3ccq]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
===Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3ccq]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CCQ FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18455733}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ccq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ccq OCA], [https://pdbe.org/3ccq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ccq RCSB], [https://www.ebi.ac.uk/pdbsum/3ccq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ccq ProSAT]</span></td></tr>
-
[[3ccq]] is a 30 chain structure of [[Ribosomal protein L10]], [[Ribosomal protein L11]], [[Ribosomal protein L13]], [[Ribosomal protein L14]], [[Ribosomal protein L19]], [[Ribosomal protein L2]], [[Ribosomal protein L21]], [[Ribosomal protein L3]], [[Ribosomal protein L34]], [[Ribosomal protein L4]], [[Ribosomal protein L5]], [[Ribosomal protein L6]], [[Ribosomal protein L7]] and [[Ribosome]] with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CCQ OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cc/3ccq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ccq ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ribosomal protein L10|Ribosomal protein L10]]
+
*[[Ribosome 3D structures|Ribosome 3D structures]]
-
*[[Ribosomal protein L11|Ribosomal protein L11]]
+
__TOC__
-
*[[Ribosomal protein L13|Ribosomal protein L13]]
+
</StructureSection>
-
*[[Ribosomal protein L14|Ribosomal protein L14]]
+
-
*[[Ribosomal protein L19|Ribosomal protein L19]]
+
-
*[[Ribosomal protein L2|Ribosomal protein L2]]
+
-
*[[Ribosomal protein L21|Ribosomal protein L21]]
+
-
*[[Ribosomal protein L3|Ribosomal protein L3]]
+
-
*[[Ribosomal protein L34|Ribosomal protein L34]]
+
-
*[[Ribosomal protein L4|Ribosomal protein L4]]
+
-
*[[Ribosomal protein L5|Ribosomal protein L5]]
+
-
*[[Ribosomal protein L6|Ribosomal protein L6]]
+
-
*[[Ribosomal protein L7|Ribosomal protein L7]]
+
-
*[[Ribosome|Ribosome]]
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:018455733</ref><references group="xtra"/>
+
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
-
[[Category: Blaha, G.]]
+
[[Category: Large Structures]]
-
[[Category: Gurel, G.]]
+
[[Category: Blaha G]]
-
[[Category: Genomic sequnece for r-protein]]
+
[[Category: Gurel G]]
-
[[Category: Ribosome]]
+

Current revision

Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U

PDB ID 3ccq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ccq"
Personal tools