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1ef2

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[[Image:1ef2.png|left|200px]]
 
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{{STRUCTURE_1ef2| PDB=1ef2 | SCENE= }}
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==CRYSTAL STRUCTURE OF MANGANESE-SUBSTITUTED KLEBSIELLA AEROGENES UREASE==
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<StructureSection load='1ef2' size='340' side='right'caption='[[1ef2]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF MANGANESE-SUBSTITUTED KLEBSIELLA AEROGENES UREASE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ef2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_aerogenes Klebsiella aerogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EF2 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10555581}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ef2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ef2 OCA], [https://pdbe.org/1ef2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ef2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ef2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ef2 ProSAT]</span></td></tr>
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[[1ef2]] is a 3 chain structure of [[Urease]] with sequence from [http://en.wikipedia.org/wiki/Enterobacter_aerogenes Enterobacter aerogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EF2 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/URE1_KLEAE URE1_KLEAE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/1ef2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ef2 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Urease|Urease]]
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*[[Urease 3D structures|Urease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:010555581</ref><references group="xtra"/>
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[[Category: Klebsiella aerogenes]]
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[[Category: Enterobacter aerogenes]]
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[[Category: Large Structures]]
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[[Category: Urease]]
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[[Category: Cosper NJ]]
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[[Category: Cosper, N J.]]
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[[Category: Hausinger RP]]
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[[Category: Hausinger, R P.]]
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[[Category: Karplus PA]]
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[[Category: Karplus, P A.]]
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[[Category: Pearson MA]]
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[[Category: Pearson, M A.]]
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[[Category: Scott RA]]
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[[Category: Scott, R A.]]
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[[Category: Stalhandske C]]
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[[Category: Stalhandske, C.]]
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[[Category: Yamaguchi K]]
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[[Category: Yamaguchi, K.]]
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[[Category: Alpha-beta barrel]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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Current revision

CRYSTAL STRUCTURE OF MANGANESE-SUBSTITUTED KLEBSIELLA AEROGENES UREASE

PDB ID 1ef2

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