1eli
From Proteopedia
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- | [[Image:1eli.png|left|200px]] | ||
- | + | ==COMPLEX OF MONOMERIC SARCOSINE OXIDASE WITH THE INHIBITOR PYRROLE-2-CARBOXYLATE== | |
- | + | <StructureSection load='1eli' size='340' side='right'caption='[[1eli]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1eli]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._B-0618 Bacillus sp. B-0618]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ELI FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PYC:PYRROLE-2-CARBOXYLATE'>PYC</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eli OCA], [https://pdbe.org/1eli PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eli RCSB], [https://www.ebi.ac.uk/pdbsum/1eli PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eli ProSAT]</span></td></tr> |
- | [[1eli]] is a 2 chain structure | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MSOX_BACB0 MSOX_BACB0] Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L-alanine.[HAMAP-Rule:MF_00516] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1eli_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eli ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Sarcosine oxidase|Sarcosine oxidase]] | *[[Sarcosine oxidase|Sarcosine oxidase]] | ||
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Bacillus sp. B-0618]] | |
- | [[Category: Bacillus sp.]] | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Chen Z-W]] |
- | [[Category: Chen | + | [[Category: Jorns MS]] |
- | [[Category: Jorns | + | [[Category: Mathews FS]] |
- | [[Category: Mathews | + | [[Category: Trickey P]] |
- | [[Category: Trickey | + | [[Category: Wagner MA]] |
- | [[Category: Wagner | + | |
- | + | ||
- | + | ||
- | + |
Current revision
COMPLEX OF MONOMERIC SARCOSINE OXIDASE WITH THE INHIBITOR PYRROLE-2-CARBOXYLATE
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