2lw4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2lw4 is ON HOLD Authors: Eletsky, A., Wang, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T. Descri...) |
|||
| (10 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B== | |
| - | + | <StructureSection load='2lw4' size='340' side='right'caption='[[2lw4]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2lw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw4 OCA], [https://pdbe.org/2lw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw4 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TCEA2_HUMAN TCEA2_HUMAN] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.<ref>PMID:12034815</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Acton TB]] | ||
| + | [[Category: Eletsky A]] | ||
| + | [[Category: Everett JK]] | ||
| + | [[Category: Janjua H]] | ||
| + | [[Category: Kohan E]] | ||
| + | [[Category: Montelione GT]] | ||
| + | [[Category: Szyperski T]] | ||
| + | [[Category: Wang D]] | ||
| + | [[Category: Xiao R]] | ||
Current revision
Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B
| |||||||||||
Categories: Homo sapiens | Large Structures | Acton TB | Eletsky A | Everett JK | Janjua H | Kohan E | Montelione GT | Szyperski T | Wang D | Xiao R
