2lw7
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==NMR solution structure of human HisRS splice variant== |
| + | <StructureSection load='2lw7' size='340' side='right'caption='[[2lw7]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2lw7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw7 OCA], [https://pdbe.org/2lw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/HARS1_HUMAN HARS1_HUMAN] Usher syndrome type 3;Autosomal dominant Charcot-Marie-Tooth disease type 2W. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HARS1_HUMAN HARS1_HUMAN] Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) (PubMed:29235198). Plays a role in axon guidance (PubMed:26072516).<ref>PMID:26072516</ref> <ref>PMID:29235198</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schimmel P]] | ||
| + | [[Category: Wei Z]] | ||
| + | [[Category: Wu J]] | ||
| + | [[Category: Ye F]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
NMR solution structure of human HisRS splice variant
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Categories: Homo sapiens | Large Structures | Schimmel P | Wei Z | Wu J | Ye F | Zhang M
