2lw9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR solution structure of Myo10 anti-CC== | |
| + | <StructureSection load='2lw9' size='340' side='right'caption='[[2lw9]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2lw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw9 OCA], [https://pdbe.org/2lw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw9 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYO10_HUMAN MYO10_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).<ref>PMID:16894163</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Myosin 3D Structures|Myosin 3D Structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lu Q]] | ||
| + | [[Category: Ye F]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
NMR solution structure of Myo10 anti-CC
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Categories: Homo sapiens | Large Structures | Lu Q | Ye F | Zhang M
