4b43
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4b43 is ON HOLD until Paper Publication Authors: Simonetti, A., Urzhumtsev, A., Klaholz, B.P. Description: Bacterial translation initiation factor ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A== | |
| - | + | <StructureSection load='4b43' size='340' side='right'caption='[[4b43]], [[Resolution|resolution]] 1.94Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4b43]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B43 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.937Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b43 OCA], [https://pdbe.org/4b43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b43 RCSB], [https://www.ebi.ac.uk/pdbsum/4b43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b43 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus HB8]] | ||
| + | [[Category: Klaholz BP]] | ||
| + | [[Category: Simonetti A]] | ||
| + | [[Category: Urzhumtsev A]] | ||
Current revision
Bacterial translation initiation factor IF2 (1-363), apo form, double mutant K86L H130A
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