This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4ehu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:01, 14 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4ehu.jpg|left|200px]]
 
-
{{STRUCTURE_4ehu| PDB=4ehu | SCENE= }}
+
==Activator of the 2-Hydroxyisocaproyl-CoA Dehydratase from Clostridium difficile with bound ADPNP==
-
 
+
<StructureSection load='4ehu' size='340' side='right'caption='[[4ehu]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
===Activator of the 2-Hydroxyisocaproyl-CoA Dehydratase from Clostridium difficile with bound ADPNP===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4ehu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridioides_difficile Clostridioides difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EHU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EHU FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22827463}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ehu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ehu OCA], [https://pdbe.org/4ehu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ehu RCSB], [https://www.ebi.ac.uk/pdbsum/4ehu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ehu ProSAT]</span></td></tr>
-
[[4ehu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_difficile Clostridium difficile]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EHU OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/HADI_CLODI HADI_CLODI] Involved in the reductive branch of L-leucine fermentation. Required for the activation of (R)-2-hydroxyisocaproyl-CoA dehydratase. The reduced activator transfers one electron to the dehydratase concomitant with hydrolysis of ATP. This protein is extremely sensitive towards oxygen.<ref>PMID:15654892</ref> <ref>PMID:22827463</ref>
-
<ref group="xtra">PMID:022827463</ref><references group="xtra"/>
+
== References ==
-
[[Category: Clostridium difficile]]
+
<references/>
-
[[Category: Dobbek, H.]]
+
__TOC__
-
[[Category: Knauer, S H.]]
+
</StructureSection>
-
[[Category: 2-hydroxyisocaproyl-coa dehydratase binding]]
+
[[Category: Clostridioides difficile]]
-
[[Category: Actin fold]]
+
[[Category: Large Structures]]
-
[[Category: Atp/adp binding]]
+
[[Category: Dobbek H]]
-
[[Category: Atpase]]
+
[[Category: Knauer SH]]
-
[[Category: Electron transfer]]
+
-
[[Category: Electron transport]]
+

Current revision

Activator of the 2-Hydroxyisocaproyl-CoA Dehydratase from Clostridium difficile with bound ADPNP

PDB ID 4ehu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4ehu"
Personal tools