3uhm

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[[Image:3uhm.png|left|200px]]
 
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{{STRUCTURE_3uhm| PDB=3uhm | SCENE= }}
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==UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor==
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<StructureSection load='3uhm' size='340' side='right'caption='[[3uhm]], [[Resolution|resolution]] 1.26&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3uhm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UHM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.26&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=RFN:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-(2-OXO-4-PHENYLPYRIDIN-1(2H)-YL)BUTANAMIDE'>RFN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uhm OCA], [https://pdbe.org/3uhm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uhm RCSB], [https://www.ebi.ac.uk/pdbsum/3uhm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uhm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
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===UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor===
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==See Also==
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
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{{ABSTRACT_PUBMED_22257165}}
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures|UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3uhm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UHM OCA].
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:022257165</ref><references group="xtra"/>
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Liu, S.]]
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[[Category: Liu S]]
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[[Category: Montgomery, J.]]
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[[Category: Montgomery J]]
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[[Category: Amidohydrolase]]
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[[Category: Anti-bacterial agent]]
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[[Category: Bacteria]]
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[[Category: Catalytic domain]]
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[[Category: Drug design]]
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[[Category: Enzyme inhibitor]]
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[[Category: Gram negative]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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Current revision

UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase in complex with inhibitor

PDB ID 3uhm

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