2vph
From Proteopedia
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- | [[Image:2vph.png|left|200px]] | ||
- | + | ==Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain== | |
- | + | <StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPH FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [https://pdbe.org/2vph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [https://www.ebi.ac.uk/pdbsum/2vph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr> |
- | [[2vph]] is a 2 chain structure | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PTN4_HUMAN PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/2vph_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vph ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
- | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] |
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
- | [[Category: Bountra | + | [[Category: Bountra C]] |
- | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown N]] |
- | + | [[Category: Edwards A]] | |
- | [[Category: Edwards | + | [[Category: Elkins JM]] |
- | [[Category: Elkins | + | [[Category: Filippakopoulos P]] |
- | [[Category: Filippakopoulos | + | [[Category: Kavanagh K]] |
- | [[Category: Kavanagh | + | [[Category: Knapp S]] |
- | [[Category: Knapp | + | [[Category: Pike ACW]] |
- | [[Category: Pike | + | [[Category: Roos AK]] |
- | [[Category: Roos | + | [[Category: Wang J]] |
- | [[Category: Wang | + | [[Category: Weigelt J]] |
- | [[Category: Weigelt | + | [[Category: Von Delft F]] |
- | [[Category: | + | |
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Current revision
Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown N | Edwards A | Elkins JM | Filippakopoulos P | Kavanagh K | Knapp S | Pike ACW | Roos AK | Wang J | Weigelt J | Von Delft F