1dma
From Proteopedia
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| - | [[Image:1dma.png|left|200px]] | ||
| - | + | ==DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH NICOTINAMIDE AND AMP== | |
| + | <StructureSection load='1dma' size='340' side='right'caption='[[1dma]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1dma]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DMA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dma OCA], [https://pdbe.org/1dma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dma RCSB], [https://www.ebi.ac.uk/pdbsum/1dma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dma ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TOXA_PSEAE TOXA_PSEAE] An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38.<ref>PMID:18276581</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Exotoxin 3D structures|Exotoxin 3D structures]] | |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | [[ | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | == | + | |
| - | < | + | |
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
| - | [[Category: Benhar | + | [[Category: Benhar I]] |
| - | [[Category: Davies | + | [[Category: Davies D]] |
| - | [[Category: Dyda | + | [[Category: Dyda F]] |
| - | [[Category: Li | + | [[Category: Li M]] |
| - | [[Category: Pastan | + | [[Category: Pastan I]] |
| - | + | ||
Current revision
DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH NICOTINAMIDE AND AMP
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