1o06

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[[Image:1o06.png|left|200px]]
 
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{{STRUCTURE_1o06| PDB=1o06 | SCENE= }}
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==Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM)==
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<StructureSection load='1o06' size='340' side='right'caption='[[1o06]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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===Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1o06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1O06 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12750381}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1o06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o06 OCA], [https://pdbe.org/1o06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1o06 RCSB], [https://www.ebi.ac.uk/pdbsum/1o06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1o06 ProSAT]</span></td></tr>
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[[1o06]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O06 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/VPS27_YEAST VPS27_YEAST] Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. Controls exit from the prevacuolar compartment (PVC) in both the forward direction to the vacuole and the return to the Golgi. Allows VPS10 to return to the (trans-Golgi network) TGN from the PVC. Might also function as an alternate adapter in the COPIb clathrin-like coat.<ref>PMID:3062374</ref> <ref>PMID:1493335</ref> <ref>PMID:8649377</ref> <ref>PMID:9015300</ref> <ref>PMID:9265642</ref> <ref>PMID:11208109</ref> <ref>PMID:11416128</ref> <ref>PMID:12055639</ref> <ref>PMID:11872141</ref> <ref>PMID:12900393</ref> <ref>PMID:14581452</ref> <ref>PMID:15166140</ref> <ref>PMID:15107463</ref> <ref>PMID:15086794</ref> <ref>PMID:17101773</ref> <ref>PMID:17135292</ref>
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<ref group="xtra">PMID:012750381</ref><references group="xtra"/>
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== References ==
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[[Category: Alam, S L.]]
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<references/>
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[[Category: Fisher, R D.]]
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__TOC__
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[[Category: Higginson, D S.]]
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</StructureSection>
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[[Category: Hill, C P.]]
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[[Category: Large Structures]]
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[[Category: Myszka, D.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Rich, R.]]
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[[Category: Alam SL]]
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[[Category: Sundquist, W I.]]
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[[Category: Fisher RD]]
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[[Category: Wang, B.]]
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[[Category: Higginson DS]]
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[[Category: Alpha-helix]]
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[[Category: Hill CP]]
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[[Category: Coiled-coil]]
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[[Category: Myszka D]]
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[[Category: Tetramer]]
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[[Category: Rich R]]
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[[Category: Transport protein]]
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[[Category: Sundquist WI]]
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[[Category: Wang B]]

Current revision

Crystal structure of the Vps27p Ubiquitin Interacting Motif (UIM)

PDB ID 1o06

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