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2a26
From Proteopedia
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| - | [[Image:2a26.png|left|200px]] | ||
| - | + | ==Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein== | |
| - | + | <StructureSection load='2a26' size='340' side='right'caption='[[2a26]], [[Resolution|resolution]] 1.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2a26]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A26 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a26 OCA], [https://pdbe.org/2a26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a26 RCSB], [https://www.ebi.ac.uk/pdbsum/2a26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a26 ProSAT]</span></td></tr> |
| - | [[2a26]] is a 3 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/CYBP_HUMAN CYBP_HUMAN] May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).<ref>PMID:16085652</ref> |
| - | < | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Ely | + | [[Category: Large Structures]] |
| - | [[Category: Fukushima | + | [[Category: Ely KR]] |
| - | [[Category: Leone | + | [[Category: Fukushima T]] |
| - | [[Category: Li | + | [[Category: Leone M]] |
| - | [[Category: Liddington | + | [[Category: Li C]] |
| - | [[Category: Matsuzawa | + | [[Category: Liddington RC]] |
| - | [[Category: Olson | + | [[Category: Matsuzawa S]] |
| - | [[Category: Pellecchia | + | [[Category: Olson AJ]] |
| - | [[Category: Preece | + | [[Category: Pellecchia M]] |
| - | [[Category: Reed | + | [[Category: Preece NE]] |
| - | [[Category: Santelli | + | [[Category: Reed JC]] |
| - | + | [[Category: Santelli E]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein
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Categories: Homo sapiens | Large Structures | Ely KR | Fukushima T | Leone M | Li C | Liddington RC | Matsuzawa S | Olson AJ | Pellecchia M | Preece NE | Reed JC | Santelli E
