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4afs

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[[Image:4afs.png|left|200px]]
 
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{{STRUCTURE_4afs| PDB=4afs | SCENE= }}
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==Human Chymase - Fynomer Complex==
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<StructureSection load='4afs' size='340' side='right'caption='[[4afs]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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===Human Chymase - Fynomer Complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4afs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AFS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22653218}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4afs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afs OCA], [https://pdbe.org/4afs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4afs RCSB], [https://www.ebi.ac.uk/pdbsum/4afs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4afs ProSAT]</span></td></tr>
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[[4afs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFS OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
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<ref group="xtra">PMID:022653218</ref><references group="xtra"/>
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__TOC__
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[[Category: Chymase]]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Synthetic construct]]
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[[Category: Banner, D W.]]
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[[Category: Banner DW]]
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[[Category: Batey, S.]]
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[[Category: Batey S]]
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[[Category: Benz, J.]]
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[[Category: Benz J]]
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[[Category: Bertschinger, J.]]
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[[Category: Bertschinger J]]
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[[Category: Brack, S.]]
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[[Category: Brack S]]
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[[Category: Grabulovski, D.]]
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[[Category: Grabulovski D]]
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[[Category: Hennig, M.]]
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[[Category: Hennig M]]
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[[Category: Huber, W.]]
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[[Category: Huber W]]
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[[Category: Joseph, C.]]
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[[Category: Joseph C]]
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[[Category: Kloosters, A Van Der.]]
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[[Category: Rufer A]]
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[[Category: Rufer, A.]]
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[[Category: Schlatter D]]
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[[Category: Schlatter, D.]]
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[[Category: Van Der Kloosters A]]
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[[Category: Weber, M.]]
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[[Category: Weber M]]
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[[Category: Hydrolase-de novo protein complex]]
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[[Category: Inhibitor]]
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[[Category: Serine protease]]
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Current revision

Human Chymase - Fynomer Complex

PDB ID 4afs

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