4ezr

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'''Unreleased structure'''
 
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The entry 4ezr is ON HOLD until Paper Publication
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==Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)==
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<StructureSection load='4ezr' size='340' side='right'caption='[[4ezr]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ezr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EZR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ezr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ezr OCA], [https://pdbe.org/4ezr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ezr RCSB], [https://www.ebi.ac.uk/pdbsum/4ezr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ezr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
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Authors: Zahn, M., Straeter, N.
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==See Also==
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*[[Heat Shock Protein structures|Heat Shock Protein structures]]
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Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)
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__TOC__
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</StructureSection>
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[[Category: Drosophila melanogaster]]
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Straeter N]]
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[[Category: Zahn M]]

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Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)

PDB ID 4ezr

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