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4gie
From Proteopedia
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| - | [[Image:4gie.jpg|left|200px]] | ||
| - | + | ==Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP== | |
| + | <StructureSection load='4gie' size='340' side='right'caption='[[4gie]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gie]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GIE FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gie OCA], [https://pdbe.org/4gie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gie RCSB], [https://www.ebi.ac.uk/pdbsum/4gie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gie ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGFS_TRYCC PGFS_TRYCC] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde (By similarity). | ||
| - | == | + | ==See Also== |
| - | + | *[[Prostaglandin F synthase 3D structures|Prostaglandin F synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | [[ | + | [[Category: Large Structures]] |
| - | + | [[Category: Trypanosoma cruzi strain CL Brener]] | |
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Current revision
Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP
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