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1j2z

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[[Image:1j2z.jpg|left|200px]]<br /><applet load="1j2z" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1j2z, resolution 2.10&Aring;" />
 
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'''Crystal structure of UDP-N-acetylglucosamine acyltransferase'''<br />
 
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==About this Structure==
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==Crystal structure of UDP-N-acetylglucosamine acyltransferase==
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1J2Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] with <scene name='pdbligand=SOG:'>SOG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=TLA:'>TLA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine_O-acyltransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.129 2.3.1.129] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2Z OCA].
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<StructureSection load='1j2z' size='340' side='right'caption='[[1j2z]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1j2z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SOG:2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL'>SOG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2z OCA], [https://pdbe.org/1j2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2z RCSB], [https://www.ebi.ac.uk/pdbsum/1j2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LPXA_HELPY LPXA_HELPY] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00387]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j2z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j2z ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structure of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori., Lee BI, Suh SW, Proteins. 2003 Nov 15;53(3):772-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14579368 14579368]
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*[[UDP-N-acetylglucosamine acyltransferase|UDP-N-acetylglucosamine acyltransferase]]
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[[Category: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase]]
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__TOC__
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</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Lee, B I.]]
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[[Category: Lee BI]]
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[[Category: Suh, S W.]]
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[[Category: Suh SW]]
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[[Category: SO4]]
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[[Category: SOG]]
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[[Category: TLA]]
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[[Category: left-handed beta-helix structure]]
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[[Category: lpxa]]
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[[Category: udp-n-acetylglucosamine acyltransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:18:21 2008''
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Current revision

Crystal structure of UDP-N-acetylglucosamine acyltransferase

PDB ID 1j2z

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