1j2y

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[[Image:1j2y.jpg|left|200px]]<br /><applet load="1j2y" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1j2y, resolution 2.60&Aring;" />
 
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'''Crystal structure of the type II 3-dehydroquinase'''<br />
 
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==About this Structure==
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==Crystal structure of the type II 3-dehydroquinase==
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1J2Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori] with <scene name='pdbligand=DQA:'>DQA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2Y OCA].
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<StructureSection load='1j2y' size='340' side='right'caption='[[1j2y]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1j2y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2Y FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DQA:1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC+ACID'>DQA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2y OCA], [https://pdbe.org/1j2y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2y RCSB], [https://www.ebi.ac.uk/pdbsum/1j2y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2y ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j2/1j2y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j2y ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structure of the type II 3-dehydroquinase from Helicobacter pylori., Lee BI, Kwak JE, Suh SW, Proteins. 2003 Jun 1;51(4):616-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12784220 12784220]
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*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
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[[Category: 3-dehydroquinate dehydratase]]
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__TOC__
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</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kwak, J E.]]
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[[Category: Kwak JE]]
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[[Category: Lee, B I.]]
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[[Category: Lee BI]]
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[[Category: Suh, S W.]]
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[[Category: Suh SW]]
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[[Category: DQA]]
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[[Category: 3-dehydroquinase]]
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[[Category: lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:18:23 2008''
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Current revision

Crystal structure of the type II 3-dehydroquinase

PDB ID 1j2y

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