1j7j
From Proteopedia
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| - | [[Image:1j7j.jpg|left|200px]]<br /><applet load="1j7j" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1j7j, resolution 2.3Å" /> | ||
| - | '''Crystal Structure of the HPRT from Salmonella typhimurium'''<br /> | ||
| - | == | + | ==Crystal Structure of the HPRT from Salmonella typhimurium== |
| - | + | <StructureSection load='1j7j' size='340' side='right'caption='[[1j7j]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [ | + | <table><tr><td colspan='2'>[[1j7j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J7J FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | [ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7j OCA], [https://pdbe.org/1j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j7j RCSB], [https://www.ebi.ac.uk/pdbsum/1j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j7j ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/HPRT_SALTY HPRT_SALTY] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity). | |
| - | + | == Evolutionary Conservation == | |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j7j_consurf.spt"</scriptWhenChecked> | |
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j7j ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] | ||
| + | [[Category: Eakin AE]] | ||
| + | [[Category: Focia PJ]] | ||
| + | [[Category: Lee CC]] | ||
| + | [[Category: Spraggon G]] | ||
Current revision
Crystal Structure of the HPRT from Salmonella typhimurium
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