4enh
From Proteopedia
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- | [[Image:4enh.jpg|left|200px]] | ||
- | + | ==Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound== | |
- | + | <StructureSection load='4enh' size='340' side='right'caption='[[4enh]], [[Resolution|resolution]] 2.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4enh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ENH FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FVX:FLUVOXAMINE'>FVX</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4enh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4enh OCA], [https://pdbe.org/4enh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4enh RCSB], [https://www.ebi.ac.uk/pdbsum/4enh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4enh ProSAT]</span></td></tr> |
- | [[4enh]] is a 1 chain structure with sequence from [ | + | </table> |
- | + | == Function == | |
- | == | + | [https://www.uniprot.org/uniprot/CP46A_HUMAN CP46A_HUMAN] Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. |
- | < | + | __TOC__ |
- | [[ | + | </StructureSection> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Mast N]] |
- | [[Category: | + | [[Category: Pikuleva IA]] |
- | [[Category: | + | [[Category: Stout CD]] |
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Current revision
Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound
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