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4gnw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of nitrophorin 4 triple mutant complex with ammonia== | |
| + | <StructureSection load='4gnw' size='340' side='right'caption='[[4gnw]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GNW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NH3:AMMONIA'>NH3</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gnw OCA], [https://pdbe.org/4gnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gnw RCSB], [https://www.ebi.ac.uk/pdbsum/4gnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gnw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Nitrophorin|Nitrophorin]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rhodnius prolixus]] | ||
| + | [[Category: Issaian AV]] | ||
| + | [[Category: Montfort WR]] | ||
| + | [[Category: Weichsel A]] | ||
Current revision
Crystal structure of nitrophorin 4 triple mutant complex with ammonia
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