4e3x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:51, 14 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:4e3x.png|left|200px]]
 
-
{{STRUCTURE_4e3x| PDB=4e3x | SCENE= }}
+
==Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline==
-
 
+
<StructureSection load='4e3x' size='340' side='right'caption='[[4e3x]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
-
===Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[4e3x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E3X FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_22868767}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=16P:3,6,9,12,15,18-HEXAOXAICOSANE'>16P</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e3x OCA], [https://pdbe.org/4e3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e3x RCSB], [https://www.ebi.ac.uk/pdbsum/4e3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e3x ProSAT]</span></td></tr>
-
[[4e3x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E3X OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AL4A1_MOUSE AL4A1_MOUSE] Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity).
==See Also==
==See Also==
 +
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
*[[Pyrroline-5-carboxylate dehydrogenase|Pyrroline-5-carboxylate dehydrogenase]]
*[[Pyrroline-5-carboxylate dehydrogenase|Pyrroline-5-carboxylate dehydrogenase]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:022868767</ref><references group="xtra"/>
+
[[Category: Large Structures]]
-
[[Category: 1-pyrroline-5-carboxylate dehydrogenase]]
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Pemberton, T A.]]
+
[[Category: Pemberton TA]]
-
[[Category: Tanner, J J.]]
+
[[Category: Tanner JJ]]
-
[[Category: Amino acid metabolism]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Proline inhibition]]
+

Current revision

Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline

PDB ID 4e3x

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools