3qyb

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[[Image:3qyb.png|left|200px]]
 
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{{STRUCTURE_3qyb| PDB=3qyb | SCENE= }}
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==X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain==
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<StructureSection load='3qyb' size='340' side='right'caption='[[3qyb]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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===X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qyb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QYB FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21454505}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qyb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qyb OCA], [https://pdbe.org/3qyb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qyb RCSB], [https://www.ebi.ac.uk/pdbsum/3qyb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qyb ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[3qyb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYB OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/TBCD4_HUMAN TBCD4_HUMAN] May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake.<ref>PMID:15971998</ref> <ref>PMID:18771725</ref> <ref>PMID:22908308</ref>
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==Reference==
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== References ==
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<ref group="xtra">PMID:021454505</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Park, S Y.]]
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[[Category: Large Structures]]
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[[Category: Shoelson, S E.]]
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[[Category: Park SY]]
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[[Category: Adipocyte]]
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[[Category: Shoelson SE]]
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[[Category: Hydrolase activator]]
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[[Category: Rab]]
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[[Category: Rabgap]]
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Current revision

X-ray Crystal Structure of Human TBC1D4 (AS160) RabGAP domain

PDB ID 3qyb

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