3t3o

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[[Image:3t3o.png|left|200px]]
 
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{{STRUCTURE_3t3o| PDB=3t3o | SCENE= }}
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==Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J==
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<StructureSection load='3t3o' size='340' side='right'caption='[[3t3o]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3t3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T3O FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21893286}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t3o OCA], [https://pdbe.org/3t3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t3o RCSB], [https://www.ebi.ac.uk/pdbsum/3t3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t3o ProSAT]</span></td></tr>
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[[3t3o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb27 Thermus thermophilus hb27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3O OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/RNJ_THET2 RNJ_THET2] An RNase that has endonuclease and possibly 5'-3' exonuclease activity. Probably involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.<ref>PMID:18204464</ref>
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<ref group="xtra">PMID:021893286</ref><references group="xtra"/>
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== References ==
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[[Category: Thermus thermophilus hb27]]
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<references/>
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[[Category: Condon, C.]]
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__TOC__
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[[Category: Dorleans, A.]]
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</StructureSection>
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[[Category: Gilet, L.]]
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[[Category: Large Structures]]
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[[Category: Piton, J.]]
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[[Category: Thermus thermophilus HB27]]
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[[Category: Putzer, H.]]
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[[Category: Condon C]]
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[[Category: Sierra-Gallay, I Li de la.]]
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[[Category: Dorleans A]]
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[[Category: Zig, L.]]
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[[Category: Gilet L]]
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[[Category: 5'-3' exoribonuclease]]
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[[Category: Li de la Sierra-Gallay I]]
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[[Category: Endoribonuclease]]
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[[Category: Piton J]]
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[[Category: Hydrolase]]
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[[Category: Putzer H]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Zig L]]
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[[Category: Metal dependent hydrolase]]
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[[Category: Metallo-beta-lactamase]]
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[[Category: Protein-rna complex]]
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[[Category: Rna]]
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[[Category: Rnase j]]
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Current revision

Molecular basis for the recognition and cleavage of RNA (CUGG) by the bifunctional 5'-3' exo/endoribonuclease RNase J

PDB ID 3t3o

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