4b8w

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m (Protected "4b8w" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 4b8w is ON HOLD
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==Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form==
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<StructureSection load='4b8w' size='340' side='right'caption='[[4b8w]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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Authors: Vollmar, M., Krojer, T., Shafqat, N., Rojkova, A., Bunkoczi, G., Pike, A., Chaikuat, A., Carpenter, E., Yue, W.W., Kavanagh, K., vonDelft, F., Weigelt, J., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4b8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B8W FirstGlance]. <br>
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Description: Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8w OCA], [https://pdbe.org/4b8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b8w RCSB], [https://www.ebi.ac.uk/pdbsum/4b8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8w ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Bunkoczi G]]
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[[Category: Carpenter E]]
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[[Category: Chaikuat A]]
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[[Category: Edwards A]]
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[[Category: Kavanagh K]]
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[[Category: Krojer T]]
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[[Category: Oppermann U]]
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[[Category: Pike A]]
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[[Category: Rojkova A]]
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[[Category: Shafqat N]]
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[[Category: Vollmar M]]
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[[Category: Weigelt J]]
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[[Category: Yue WW]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form

PDB ID 4b8w

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