3sv9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:57, 1 March 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3sv9.jpg|left|200px]]
 
-
{{STRUCTURE_3sv9| PDB=3sv9 | SCENE= }}
+
==Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir==
 +
<StructureSection load='3sv9' size='340' side='right'caption='[[3sv9]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3sv9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SV9 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SV6:(1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide'>SV6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sv9 OCA], [https://pdbe.org/3sv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sv9 RCSB], [https://www.ebi.ac.uk/pdbsum/3sv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sv9 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A8DG50_9HEPC A8DG50_9HEPC]
-
===Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir===
+
==See Also==
-
 
+
*[[Virus protease 3D structures|Virus protease 3D structures]]
-
{{ABSTRACT_PUBMED_22910833}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Hepatitis C virus genotype 1a]]
-
[[3sv9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SV9 OCA].
+
[[Category: Large Structures]]
-
[[Category: Hepatitis c virus]]
+
[[Category: Romano KP]]
-
[[Category: Romano, K P.]]
+
[[Category: Schiffer CA]]
-
[[Category: Schiffer, C A.]]
+
-
[[Category: Drug design]]
+
-
[[Category: Drug resistance]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrolase-inhibitor complex]]
+
-
[[Category: Protease inhibitor]]
+
-
[[Category: Serine protease]]
+
-
[[Category: Viral protein]]
+

Current revision

Crystal structure of NS3/4A protease variant A156T in complex with Telaprevir

PDB ID 3sv9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3sv9"
Personal tools