3uv3

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[[Image:3uv3.jpg|left|200px]]
 
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{{STRUCTURE_3uv3| PDB=3uv3 | SCENE= }}
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==Ec_IspH in complex with but-2-ynyl diphosphate (1086)==
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<StructureSection load='3uv3' size='340' side='right'caption='[[3uv3]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3uv3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UV3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CM:BUT-2-YN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>0CM</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uv3 OCA], [https://pdbe.org/3uv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uv3 RCSB], [https://www.ebi.ac.uk/pdbsum/3uv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uv3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref>
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===Ec_IspH in complex with but-2-ynyl diphosphate (1086)===
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==See Also==
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*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3uv3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UV3 OCA].
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__TOC__
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[[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]]
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</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bacher, A.]]
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[[Category: Large Structures]]
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[[Category: Eisenreich, W.]]
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[[Category: Bacher A]]
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[[Category: Groll, M.]]
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[[Category: Eisenreich W]]
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[[Category: Oldfield, E.]]
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[[Category: Groll M]]
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[[Category: Schulz, C.]]
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[[Category: Oldfield E]]
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[[Category: Span, I.]]
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[[Category: Schulz C]]
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[[Category: Wang, K.]]
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[[Category: Span I]]
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[[Category: Wang, W.]]
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[[Category: Wang K]]
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[[Category: Zhang, Y.]]
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[[Category: Wang W]]
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[[Category: Iron-sulfur protein]]
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[[Category: Zhang Y]]
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[[Category: Isoprenoid biosynthesis]]
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[[Category: Isph]]
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[[Category: Lytb]]
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[[Category: Non-mevalonate pathway]]
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[[Category: Oxidoreductase]]
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Current revision

Ec_IspH in complex with but-2-ynyl diphosphate (1086)

PDB ID 3uv3

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