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4dwr

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[[Image:4dwr.jpg|left|200px]]
 
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{{STRUCTURE_4dwr| PDB=4dwr | SCENE= }}
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==RNA ligase RtcB/Mn2+ complex==
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<StructureSection load='4dwr' size='340' side='right'caption='[[4dwr]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dwr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DWR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dwr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dwr OCA], [https://pdbe.org/4dwr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dwr RCSB], [https://www.ebi.ac.uk/pdbsum/4dwr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dwr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RTCB_PYRHO RTCB_PYRHO] tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as a RNA ligase with broad substrate specificity, and may function toward other RNAs (By similarity).
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===RNA ligase RtcB/Mn2+ complex===
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==See Also==
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*[[RNA ligase|RNA ligase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4dwr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWR OCA].
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Englert, M.]]
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[[Category: Englert M]]
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[[Category: Soll, D.]]
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[[Category: Soll D]]
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[[Category: Wang, J.]]
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[[Category: Wang J]]
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[[Category: Xia, S.]]
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[[Category: Xia S]]
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[[Category: Ligase]]
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[[Category: Mn2+]]
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[[Category: Rna ligase]]
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[[Category: Rtcb]]
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Current revision

RNA ligase RtcB/Mn2+ complex

PDB ID 4dwr

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