Nuclear receptor

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Current revision

the nuclear receptors facts book ^[1]

Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry 1ie8)

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↑ Vincent Laudet, Hinrich Gronemeyer, "The nuclear receptor factsbook", Publisher Academic Press, 2002

@@ Line 1: / Line 1: @@
-== Nuclear Receptor ==
+''the nuclear receptors facts book''
+<ref>Vincent Laudet, Hinrich Gronemeyer,
+"The nuclear receptor factsbook",
+Publisher Academic Press, 2002
+</ref>
-=== Structure ===
+SEE [[Nuclear receptors]]
-==== DBD (DNA Binding Domain) ====
+<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''>
-==== LBD (Ligand Binding Domain) ====
-<StructureSection load='1ie8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1ie8]])' scene=''>
-The LBD of a nuclear receptor has a common three layer sandwich
+The structure of the LBD is strongly conserved throughout the familly of nuclear receptors.
+It is a globular domain, mainly alpha
+<scene name='Nuclear_receptor/Nr-lbd-/1'>well folded</scene>
+composed of
+<scene name='Nuclear_receptor/Nr-lbd-alpha/1'>12 alpha-helices</scene>
+arranged in a three layered sandwich, and a <scene name='Nuclear_receptor/Nr-lbd-beta/1'>beta-sheet</scene>.
 </StructureSection>
+<references/>