EibD

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:02, 9 January 2020) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD ==
== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD ==
-
<StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene=''>
+
<StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene='EibD/2xqh/1'>
<!-- The line below this paragraph, {{ABSTRACT_PUBMED_21742268}}, adds the Publication Abstract to the page(as it appears on PubMed at http://www.pubmed.gov), where 21742268 is the PubMed ID number. -->
<!-- The line below this paragraph, {{ABSTRACT_PUBMED_21742268}}, adds the Publication Abstract to the page(as it appears on PubMed at http://www.pubmed.gov), where 21742268 is the PubMed ID number. -->
Line 10: Line 10:
Resolution limit: 1.99 Å <br>
Resolution limit: 1.99 Å <br>
R/R free: 0.1585/0.1855 <br>
R/R free: 0.1585/0.1855 <br>
-
<br>
+
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA].<br>
-
Asymmetric unit contains a single polypeptide chain. The biological assembly consists of three copies of the monomer related by a three fold axis.
+
 
-
EibD/2xqh/1
+
<scene name='EibD/2xqh/1'>Asymmetric unit</scene> contains a single polypeptide chain. The <scene name='EibD/2xqh_ba/3'>biological assembly</scene> consists of three copies of the monomer related by a <scene name='EibD/2xqh_ba/11'>three fold axis</scene>.
-
<scene name='EibD/2xqh_ba/3'>TextToBeDisplayed</scene>
+
 
-
<scene name='EibD/2xqh_trimer/1'>TextToBeDisplayed</scene>
+
There are five distinct domains:
-
<scene name='EibD/Test/1'>TextToBeDisplayed</scene>
+
<ul>
-
<scene name='EibD/Test1/1'>TextToBeDisplayed</scene>
+
<li>YadA-like <scene name='EibD/2xqh_ba/5'> β-roll</scene> domain;
 +
<li><scene name='EibD/2xqh_ba/6'>neck</scene> domain;
 +
<li><scene name='EibD/2xqh_ba/7'>right handed</scene> coiled-coil domain;
 +
<li><scene name='EibD/2xqh_ba/8'>mini β-sheet</scene> domain;
 +
<li><scene name='EibD/2xqh_ba/9'>left handed</scene> coiled-coil domain;
 +
</ul>
 +
 
 +
Coiled-coil features:
 +
<ul>
 +
<li> cavities
 +
<li> chloride coordination by <scene name='EibD/2xqh_ba/12'>Thr</scene> and <scene name='EibD/2xqh_ba/13'>Asn</scene> residues.
 +
</ul>
-
[[2xqh]] is a single chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA].
 
== General information ==
== General information ==
Antibodies: [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 RCSB PDB Molecule of the Month by David Goodsell] <ref>September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9</ref>
Antibodies: [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 RCSB PDB Molecule of the Month by David Goodsell] <ref>September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9</ref>

Current revision

Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD

Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry 2xqh)

Drag the structure with the mouse to rotate

Primery reference

  • Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A. The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins. Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268 doi:10.1016/j.str.2011.03.021
  1. September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9

Proteopedia Page Contributors and Editors (what is this?)

Andrzej Lyskowski, Michal Harel

Personal tools