EibD
From Proteopedia
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== Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD == | == Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD == | ||
- | <StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene=''> | + | <StructureSection load='2xqh' size='350' side='right' caption='Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD (PDB entry [[2xqh]])' scene='EibD/2xqh/1'> |
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Resolution limit: 1.99 Å <br> | Resolution limit: 1.99 Å <br> | ||
R/R free: 0.1585/0.1855 <br> | R/R free: 0.1585/0.1855 <br> | ||
- | <br> | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA].<br> |
- | Asymmetric unit contains a single polypeptide chain. The biological assembly consists of three copies of the monomer related by a three fold axis. | + | |
- | EibD/ | + | <scene name='EibD/2xqh/1'>Asymmetric unit</scene> contains a single polypeptide chain. The <scene name='EibD/2xqh_ba/3'>biological assembly</scene> consists of three copies of the monomer related by a <scene name='EibD/2xqh_ba/11'>three fold axis</scene>. |
- | <scene name='EibD/2xqh_ba/ | + | |
- | <scene name='EibD/ | + | There are five distinct domains: |
- | <scene name='EibD/ | + | <ul> |
- | <scene name='EibD/ | + | <li>YadA-like <scene name='EibD/2xqh_ba/5'> β-roll</scene> domain; |
+ | <li><scene name='EibD/2xqh_ba/6'>neck</scene> domain; | ||
+ | <li><scene name='EibD/2xqh_ba/7'>right handed</scene> coiled-coil domain; | ||
+ | <li><scene name='EibD/2xqh_ba/8'>mini β-sheet</scene> domain; | ||
+ | <li><scene name='EibD/2xqh_ba/9'>left handed</scene> coiled-coil domain; | ||
+ | </ul> | ||
+ | |||
+ | Coiled-coil features: | ||
+ | <ul> | ||
+ | <li> cavities | ||
+ | <li> chloride coordination by <scene name='EibD/2xqh_ba/12'>Thr</scene> and <scene name='EibD/2xqh_ba/13'>Asn</scene> residues. | ||
+ | </ul> | ||
- | [[2xqh]] is a single chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQH OCA]. | ||
== General information == | == General information == | ||
Antibodies: [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 RCSB PDB Molecule of the Month by David Goodsell] <ref>September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9</ref> | Antibodies: [http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9 RCSB PDB Molecule of the Month by David Goodsell] <ref>September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9</ref> |
Current revision
Crystal structure of an immunoglobulin-binding fragment of the trimeric autotransporter adhesin (TAA) EibD
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Primery reference
- Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A. The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins. Structure. 2011 Jul 13;19(7):1021-30. PMID:21742268 doi:10.1016/j.str.2011.03.021
- ↑ September 2001 Molecule of the Month by David Goodsell http://dx.doi.org/10.2210/rcsb_pdb/mom_2001_9