3j25
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis for TetM-mediated tetracycline resistance== | |
| - | + | <SX load='3j25' size='340' side='right' viewer='molstar' caption='[[3j25]], [[Resolution|resolution]] 7.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3j25]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J25 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j25 OCA], [https://pdbe.org/3j25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j25 RCSB], [https://www.ebi.ac.uk/pdbsum/3j25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j25 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TET1_ENTFL TET1_ENTFL] Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes. | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Enterococcus faecalis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Beckmann R]] | ||
| + | [[Category: Berninghausen O]] | ||
| + | [[Category: Doenhoefer A]] | ||
| + | [[Category: Franckenberg S]] | ||
| + | [[Category: Wickles S]] | ||
| + | [[Category: Wilson DN]] | ||
Current revision
Structural basis for TetM-mediated tetracycline resistance
| |||||||||
