4fdl

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[[Image:4fdl.png|left|200px]]
 
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{{STRUCTURE_4fdl| PDB=4fdl | SCENE= }}
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==Crystal structure of Caspase-7==
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<StructureSection load='4fdl' size='340' side='right'caption='[[4fdl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4fdl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FDL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fdl OCA], [https://pdbe.org/4fdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fdl RCSB], [https://www.ebi.ac.uk/pdbsum/4fdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fdl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
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===Crystal structure of Caspase-7===
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==See Also==
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*[[Caspase 3D structures|Caspase 3D structures]]
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{{ABSTRACT_PUBMED_22795132}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[4fdl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDL OCA].
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==Reference==
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<ref group="xtra">PMID:022795132</ref><references group="xtra"/>
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[[Category: Caspase-7]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kabaleeswaran, V.]]
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[[Category: Large Structures]]
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[[Category: Central cavity]]
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[[Category: Kabaleeswaran V]]
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[[Category: Cysteine protease]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of Caspase-7

PDB ID 4fdl

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