3utd

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[[Image:3utd.png|left|200px]]
 
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{{STRUCTURE_3utd| PDB=3utd | SCENE= }}
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==Ec_IspH in complex with 4-oxopentyl diphosphate==
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<StructureSection load='3utd' size='340' side='right'caption='[[3utd]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3utd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UTD FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0CJ:4-OXOPENTYL+TRIHYDROGEN+DIPHOSPHATE'>0CJ</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3utd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3utd OCA], [https://pdbe.org/3utd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3utd RCSB], [https://www.ebi.ac.uk/pdbsum/3utd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3utd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ISPH_ECOLI ISPH_ECOLI] Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Is also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with RelA to maintain it in an inactive form during normal growth.<ref>PMID:19569147</ref> <ref>PMID:20080550</ref> <ref>PMID:22137895</ref>
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===Ec_IspH in complex with 4-oxopentyl diphosphate===
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==See Also==
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*[[4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures|4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3D structures]]
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{{ABSTRACT_PUBMED_22948824}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[3utd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UTD OCA].
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</StructureSection>
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[[Category: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli]]
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[[Category: Large Structures]]
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[[Category: Bacher, A.]]
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[[Category: Bacher A]]
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[[Category: Eisenreich, W.]]
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[[Category: Eisenreich W]]
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[[Category: Groll, M.]]
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[[Category: Groll M]]
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[[Category: Oldfield, E.]]
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[[Category: Oldfield E]]
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[[Category: Schulz, C.]]
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[[Category: Schulz C]]
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[[Category: Span, I.]]
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[[Category: Span I]]
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[[Category: Wang, K.]]
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[[Category: Wang K]]
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[[Category: Wang, W.]]
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[[Category: Wang W]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang Y]]
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[[Category: Iron-sulfur protein]]
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[[Category: Isoprenoid biosynthesis]]
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[[Category: Isph]]
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[[Category: Lytb]]
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[[Category: Non-mevalonate pathway]]
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[[Category: Oxidoreductase]]
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Current revision

Ec_IspH in complex with 4-oxopentyl diphosphate

PDB ID 3utd

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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