4edl

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[[Image:4edl.png|left|200px]]
 
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{{STRUCTURE_4edl| PDB=4edl | SCENE= }}
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==Crystal structure of beta-parvin CH2 domain==
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<StructureSection load='4edl' size='340' side='right'caption='[[4edl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4edl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EDL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4edl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edl OCA], [https://pdbe.org/4edl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4edl RCSB], [https://www.ebi.ac.uk/pdbsum/4edl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4edl ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PARVB_HUMAN PARVB_HUMAN] Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.<ref>PMID:11402068</ref> <ref>PMID:15005707</ref> <ref>PMID:15284246</ref> <ref>PMID:15159419</ref> <ref>PMID:18325335</ref>
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===Crystal structure of beta-parvin CH2 domain===
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==See Also==
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*[[Parvin 3D structures|Parvin 3D structures]]
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{{ABSTRACT_PUBMED_22869380}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[4edl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDL OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Boggon, T J.]]
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[[Category: Large Structures]]
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[[Category: Calderwood, D A.]]
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[[Category: Boggon TJ]]
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[[Category: Chayen, N E.]]
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[[Category: Calderwood DA]]
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[[Category: Draheim, K M.]]
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[[Category: Chayen NE]]
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[[Category: Li, X.]]
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[[Category: Draheim KM]]
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[[Category: Stiegler, A L.]]
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[[Category: Li X]]
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[[Category: Adaptor protein]]
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[[Category: Stiegler AL]]
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[[Category: Calponin homology domain]]
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[[Category: Focal adhesion]]
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[[Category: Integrin signaling]]
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[[Category: Ld motif]]
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[[Category: Paxillin and integrin-linked kinase]]
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[[Category: Protein-protein interaction]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of beta-parvin CH2 domain

PDB ID 4edl

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