4ewl
From Proteopedia
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| - | [[Image:4ewl.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of MshB with glycerol and Acetate bound in the active site== | |
| - | + | <StructureSection load='4ewl' size='340' side='right'caption='[[4ewl]], [[Resolution|resolution]] 1.85Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ewl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EWL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[4ewl]] is a 2 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ewl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ewl OCA], [https://pdbe.org/4ewl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ewl RCSB], [https://www.ebi.ac.uk/pdbsum/4ewl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ewl ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MSHB_MYCTU MSHB_MYCTU] Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol (MSH) biosynthesis pathway. Shows some amidase activity toward S-conjugates of mycothiol.<ref>PMID:11092856</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | + | [[Category: Broadley SG]] | |
| - | [[Category: Broadley | + | [[Category: Marakalala MJ]] |
| - | [[Category: Marakalala | + | [[Category: Sewell BT]] |
| - | [[Category: Sewell | + | [[Category: Steenkamp DJ]] |
| - | [[Category: Steenkamp | + | [[Category: Weber BW]] |
| - | [[Category: Weber | + | |
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Current revision
Crystal Structure of MshB with glycerol and Acetate bound in the active site
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