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4f4c
From Proteopedia
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| - | [[Image:4f4c.jpg|left|200px]] | ||
| - | + | ==The Crystal Structure of the Multi-Drug Transporter== | |
| - | + | <StructureSection load='4f4c' size='340' side='right'caption='[[4f4c]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4f4c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F4C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0SA:UNDECYL+4-O-ALPHA-D-GLUCOPYRANOSYL-1-THIO-BETA-D-GLUCOPYRANOSIDE'>0SA</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[4f4c]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f4c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4c OCA], [https://pdbe.org/4f4c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f4c RCSB], [https://www.ebi.ac.uk/pdbsum/4f4c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4c ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGP1_CAEEL PGP1_CAEEL] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Chen J]] |
| - | [[Category: Jin | + | [[Category: Jin MS]] |
| - | [[Category: Oldham | + | [[Category: Oldham ML]] |
| - | [[Category: Zhang | + | [[Category: Zhang Q]] |
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Current revision
The Crystal Structure of the Multi-Drug Transporter
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