This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2xyk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:41, 20 December 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2xyk.png|left|200px]]
 
-
{{STRUCTURE_2xyk| PDB=2xyk | SCENE= }}
+
==Group II 2-on-2 Hemoglobin from the Plant Pathogen Agrobacterium tumefaciens==
 +
<StructureSection load='2xyk' size='340' side='right'caption='[[2xyk]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[2xyk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XYK FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xyk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xyk OCA], [https://pdbe.org/2xyk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xyk RCSB], [https://www.ebi.ac.uk/pdbsum/2xyk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xyk ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q7CX73_AGRFC Q7CX73_AGRFC]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Within the 2/2 hemoglobin sub-family, no group II 2/2Hbs from proteobacteria have been so far studied. Here we present the first structural characterization of a group II 2/2Hb from the soil and phytopathogenic bacterium Agrobacterium tumefaciens (At-2/2HbO). The crystal structure of ferric At-2/2HbO (reported at 2.1A resolution) shows the location of specific/unique heme distal site residues (e.g., His(42)CD1, a residue distinctive of proteobacteria group II 2/2Hbs) that surround a heme-liganded water molecule. A highly intertwined hydrogen-bonded network, involving residues Tyr(26)B10, His(42)CD1, Ser(49)E7, Trp(93)G8, and three distal site water molecules, stabilizes the heme-bound ligand. Such a structural organization suggests a path for diatomic ligand diffusion to/from the heme. Neither a similar distal site structuring effect nor the presence of distal site water molecules has been so far observed in group I and group III 2/2Hbs, thus adding new distinctive information to the complex picture of currently available 2/2Hb structural and functional data.
-
===Group II 2-on-2 Hemoglobin from the Plant Pathogen Agrobacterium tumefaciens===
+
Structural characterization of a group II 2/2 hemoglobin from the plant pathogen Agrobacterium tumefaciens.,Pesce A, Nardini M, Labarre M, Richard C, Wittenberg JB, Wittenberg BA, Guertin M, Bolognesi M Biochim Biophys Acta. 2010 Nov 9. PMID:21070893<ref>PMID:21070893</ref>
-
{{ABSTRACT_PUBMED_21070893}}
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
==About this Structure==
+
<div class="pdbe-citations 2xyk" style="background-color:#fffaf0;"></div>
-
[[2xyk]] is a 2 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XYK OCA].
+
==See Also==
==See Also==
-
*[[Hemoglobin|Hemoglobin]]
+
*[[Hemoglobin 3D structures|Hemoglobin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:021070893</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
[[Category: Agrobacterium tumefaciens]]
[[Category: Agrobacterium tumefaciens]]
-
[[Category: Bolognesi, M.]]
+
[[Category: Large Structures]]
-
[[Category: Guertin, M.]]
+
[[Category: Bolognesi M]]
-
[[Category: Labarre, M.]]
+
[[Category: Guertin M]]
-
[[Category: Nardini, M.]]
+
[[Category: LaBarre M]]
-
[[Category: Pesce, A.]]
+
[[Category: Nardini M]]
-
[[Category: Richard, C.]]
+
[[Category: Pesce A]]
-
[[Category: Wittenberg, B A.]]
+
[[Category: Richard C]]
-
[[Category: Wittenberg, J B.]]
+
[[Category: Wittenberg BA]]
-
[[Category: 2/2 hemoglobin]]
+
[[Category: Wittenberg JB]]
-
[[Category: Oxygen storage-transport complex]]
+

Current revision

Group II 2-on-2 Hemoglobin from the Plant Pathogen Agrobacterium tumefaciens

PDB ID 2xyk

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xyk"
Personal tools